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doctorforever
Forum Junior Topics: 91 Posts: 276 |
which virus has such a high incidence of genetic drift that more than one antigenic variant can be isolated from most infected individuals? 1-adenovirus 2-herpes 3-HIV 4-influenza virus 5-polio answer given is HIV why also influenza can not be correct? we have genetic drift(beside sifting) in influenza which is responsible for epidemic influenza.
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indsha008
| Forum Junior Topics: 8 Posts: 60
Yes, I agree with you. I think I saw this question in Kaplan book itself. Influenza is right answer too. Basically, the question is a sub-standard one and Kaplan does that too often. DOnt worrry !! On Jun 27, 2010 - 12:25 PM, doctorforever responded: THANKS FOR REPLYING YES IT IS FROM KAPLAN BOOK
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Jackofknives
| Cuddle bear inside  Topics: 101 Posts: 890
HIV is the right answer. All viruses can potentially undergo antigenic drift, except Polio (one of the reasons why Polio vaccine is so effective). But, HIV is famously known for its antigenic drift b/c HIV is piss-poor at proofreading. Influenza is mostly known for its antigenic shift.
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indsha008
| Forum Junior Topics: 8 Posts: 60
I wonder if question asked which organism is famous for what. And influenza is big time wellknown org for both - shift and drift. It's just a poor question. No offense meant. Just wanted to clarify.
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Jackofknives
| Cuddle bear inside Topics: 101 Posts: 890
HIV is the only virus that infects one person, mutate extensively in that person, then show up as multiple strains later on in that very same person - i.e. show up as more than one antigenic variant in the very same patient.
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doctorforever
| Forum Junior Topics: 91 Posts: 276
thanks guys. i just think it is not a well designed question ,in my idea both should be considered for Ag drift
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tummynun
| Forum Newbie Topics: 2 Posts: 6
ya... HIV is absolutely correct as the question asked is about getting multiple types of viruses from same patient... In case of influenza, its during transmission that the drift occurs....hence you find only one type of organism in 1 patient
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mohammem
| Forum Newbie Topics: 2 Posts: 198
high incidence ( inluenza v.)with seasonal variation(with in one year),,,,,while HIV it take 10 years duration,,,,,,so when duration is high the incidence will be low and in Q he said(most infected indivduals-group not single),,, influ. vi. is the answer note,,incedence=no. of newcases/duration
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