Prep for USMLEPrep for USMLE
         Forum      |     Resources New Posts   |   Register   |   Login





 why hypercalcemia in hyperthyroid  



Post Reply  
  • 0/5
  • 1
  • 2
  • 3
  • 4
  • 5


Author1 post
  #1

I DO NOT UNDERSTAND WHY IN THYROTOXICOSIS WE HAVE hypercalcemia ,,,b/c thyroid hormone(t3)do both deposition and resorption so why hypercalcemia? ,please anyone one can explain ,i have posted also the abstract from pubmaed thanks

PUBMED;

Thyroid hormone (T3) is essential for normal bone growth and bone metabolism. T3 stimulates bone formation directly through T3 receptors in osteoblasts. T3 also stimulates bone resorption by osteoclasts probably secondary through osteoblasts. In thyrotoxicosis accelerated bone formation and resorption resulted in high turn-over bone loss. Bone metabolic markers elevate reflecting thyrotoxic state. Normalizing thyroid hormone level at least partially restore bone mineral content. In patients under thyroid hormone replacement therapy or TSH suppression therapy TSH and free thyroid hormones should be monitored to prevent unnecessary bone loss. Especially in postmenopausal women with thyrotoxicosis or thyroid hormone therapy the assessment of bone mineral content is required







Bookmark and Share



This thread is closed, so you cannot post a reply.



Login or Register to post messages








show Similar forum topics

Hyperthyroid patient
FM harder than IM, why or why not?
Why o why?
show Related resources









Advertise | Support | Premium | Contact