|Prep for USMLE|
|         Forum      |     Resources||New Posts   |   Register   |   Login||»  |
I DO NOT UNDERSTAND WHY IN THYROTOXICOSIS WE HAVE hypercalcemia ,,,b/c thyroid hormone(t3)do both deposition and resorption so why hypercalcemia? ,please anyone one can explain ,i have posted also the abstract from pubmaed thanks
Thyroid hormone (T3) is essential for normal bone growth and bone metabolism. T3 stimulates bone formation directly through T3 receptors in osteoblasts. T3 also stimulates bone resorption by osteoclasts probably secondary through osteoblasts. In thyrotoxicosis accelerated bone formation and resorption resulted in high turn-over bone loss. Bone metabolic markers elevate reflecting thyrotoxic state. Normalizing thyroid hormone level at least partially restore bone mineral content. In patients under thyroid hormone replacement therapy or TSH suppression therapy TSH and free thyroid hormones should be monitored to prevent unnecessary bone loss. Especially in postmenopausal women with thyrotoxicosis or thyroid hormone therapy the assessment of bone mineral content is required
This thread is closed, so you cannot post a reply.
| Similar forum topics|
FM harder than IM, why or why not?
Why o why?
| Related resources|
Advertise | Support | Premium | Contact