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RDS is a ventilation defect ,in ventilation defects giving o2 will not increase p02 ,so why we give babies with RDS o2? beside the fact that there is the risck of blindness in them???
1) RDS is due to defect in gas diffusion and supplemental oxygen improves PaO2 by increasing the A-a O2 gradient, thus increasing diffusion (Fick's law).
2) High supplemental oxygen can lead to Oxygen toxicity (ROP) etc., that is why the SaO2(saturation) in these preterm babies with RDS is maintained between 85 to 90%.
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