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Can anybody explain mechanism of postural (orthostatic) hypotension?
Thanks in advance!
I actually found the explanation at last. When position changed from sitting to standing, the blood pooled in low extremities, that decreases cardiac output. Which in turn decreases blood pressure. Under normal conditions this is compensated by reflex tachycardia and blood pressure would be normalized. But with increased age, some diseases, and use of drug altering sympathetic activity that reflex tachycardia is blocked and as result patient get postural hypotension.
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