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 Hashimoto's antibodies???  



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  #1

I am having trouble with the antibodies involved in hashimotos

Some sources say Anti-TPO are the predominant Ab, while others say anti-TG and anti-microsomal are more common.

Also, I found one source that said Anti-TG and anti-microsomal antibodies were the same thing. Can anybody clear this up for me??




  #2

antimicrosomal antibodies are anti thyroid peroxidase(not thyroglubin) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1385181/

and jcem.endojournals.org/cgi/c.../content/abstract/68/4/766

The antithyroid microsomal antibodies found in the serum of patients with autoimmune thyroid disease are directed largely, if not entirely, against thyroid peroxidase (TPO)

abiut the question that which one is dominant ,i do not know but i think anti TPO IS THE MOSt abunfdant one then anti TG then anti TSH BASED ON http://emedicine.medscape.com/article/120937-overview AND I DO NOT THINK THIS IS IMPORTANT FOR EXAM just good to know.





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