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 idiopathic precocious puberty  



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Author5 Posts
  #1

how do you diagnose and treat it? 8)




  #2

Diagnosis is by PE, development of sec. sex. charact. in girls <8yrs or boys <9 yrs.

Management depends on the cause. MCC is idiopathic and Rx is a GnRH analogue. How it works, I dont know.


  #3

Neither I can understand why use GnRH agonist for therapy. May be continuous action of the drug (versus pulsatile secretion from the body) have a role here.

GnRH stimulation test is used to confirm the diagnosis. Thanks.


  #4

Yes, GnRH is pulsed in therapy for infertility, but continuous use downregulates endogenous sex hormone synthesis, and shuts down the axis.


  #5

thanks





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