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Bela
Forum Guru  Topics: 76 Posts: 404 |
5 yo girl with developing breasts. Has large hyperpigmented macules w/ irregular margins on one side of her back. Diagnosis?
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mani
| Forum Guru  Topics: 104 Posts: 1400
adrenogenetal syndrome, i think 17 alpha hydroxylase dedficiency
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mash
| Forum Guru Topics: 147 Posts: 1299
albright syndrome?
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Bela
| Forum Guru Topics: 76 Posts: 404
Very good, mash! It is Albright's. Can u elaborate? Thnx!
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mash
| Forum Guru Topics: 147 Posts: 1299
albrights is ch by precocious puberty(autonomous endocrine hyperfunction), cafe-au-lait spots and polyostotic fibrous dysplasia. females r affected more than males changes in ovary, bone, and skin tissue are most common, other endocrine and nonendocrine tissues also may be affected, including the adrenal, thyroid, pituitary, liver, and heart. The most common form of autonomous endocrine hyperfunction in this syndrome is gonadotropin independent precocious puberty, but affected individuals also may have hyperthyroidism, hypercortisolism, pituitary gigantism, or acromegaly. Nonendocrine abnormalities in this disorder include hypophosphatemia, chronic liver disease,
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