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 PUBS  



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  #1

One of the purpose for PUBS (percutaneous umbilical blood sampling) is to detect IgM antibody. Why do we need to detect IgM antibody? IgM antibody doesn't across placeta, do they? I don't understand its useness.

Thanks in advane!




  #2

when the infection crosses transplacentally foetus produces igM so we will know that the foetus is infected for sure,
since somtimes igG crosses placenta passively from the mother does`nt give accurate picture of acute infection
i hope u got it :roll:





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