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carina
Forum Elite  Topics: 99 Posts: 200 |
11. A 2.1-cm, pigmented lesion is excised from the back of a 39-year-old female, who noticed that this lesion has become more nodular in appearance within the past 2 months. Microscopic examination of this lesion reveals a malignant melanoma, composed of epithelioid cells, that extends 2 mm down to the reticular dermis. There is a band of lymphocytes beneath the melanoma. Which of the following statements is most appropriate to make to this patient? O (A) Your body's immune system will prevent metasta- ses. O (B) The prognosis is poor. O (C) Other family members are at risk for this condition. O (D) The primary site for this lesion is probably the eye. O (E) Nevi elsewhere on your body may become malig- nant.
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match2010
| Forum Newbie  Topics: 0 Posts: 295
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brainstem
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carina
| Forum Elite Topics: 99 Posts: 200
11. (B) Extension deep into the reticular dermis is indica- tive of vertical (nodular) growth. When a melanoma exhib- its a nodular growth pattern, rather than a radial pattern, there is a high likelihood that a clone of neoplastic cells has arisen that is more aggressive and is more likely to metastasize. Although there is a lymphocytic response to this tumor, it is not sufficient to destroy or contain it completely. Most melanomas are sporadic, nonfamilial, and related to sun exposure. Melanomas of the eye are much less common than melanomas of the skin. Benign skin nevi do not have a tendency to become malignant.
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