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 Minimal change disease  



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Author2 Posts
  #1

Minimal change disease is a disease of the polyions of the glomerular bm or the epithelium?

I agree with you Bio guy, the FA guys have got it wrong-- they say loss of charge in the foot processes in the answer to this question.

Yes I checked the reference too, you are correct.



Edited by dkmj13 on Jul 12, 2008 - 4:25 PM



  #2

its the basement membrane that has the charge barrier (negativity). in MCD T-cell secretes cytokines that destroy that charge barrier. so there is selective Albumin loss in the urine.

(Ref: Rapid Review Path - Goljan)






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