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 Steroids  



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Author11 Posts
  #1

Use of prednisone in Rheum Arth is associated with this adver eff:

1. Hypocalcemia
2. Hyercalcemia
3. Hypothesion
4. Hyper K
5. Hypo K




  #2

hypo kalemia :?:


  #3

hypocalcemia why


  #4

Hypocalcemia


  #5

I thought it would be Hyper K, cuz of weak menerallo effect that glucks have. But it turned out to be Hypo Ca. But does'nt cortics activate osteoclastes and depress osteoblasts???


  #6

always go for hypocalcemia if choices like above are given...since it most commonly causes osteoporosis


  #7

can u explain better? plz


  #8

osteo results from over stimul to osteoclast and down reg of blasts.. that increases Ca in plasma.


  #9

it can cause avascular necrosis. and # due to osteoporosis.

vasculitis.med.jhu.edu/trea...treatments/prednisone.html


  #10

but if the calcium is depleted from bone, wont it be increased in blood ?


  #11

corticosteroids are known to block vitamin D activity --> inhibit intestinal absorbtion of Ca2+ --> hypocalcemia





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