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The absence of appropirate androgen signaling in patients with SMA diminishes protein synthesis, especially in muscle, contributing to decreased muscle mass. The product normally encoded by the SMA gene would be described as a

A. Tyrosine kinase
B. Zince finger protein
C. 5a-Steroid reductase
D. Serine-threonine kinase
E. Trimeric G protein



Tyrosine kinase


I thought the answer was A as well, but its actually B because all intracellular receptors for steroid hormones are zing finger proteins


Thats right...for any DNA-binding element, you need zinc-fingers.

edit: remember tyrosine kinases are membrane signallers, and this is a steroid, which will bind to a cytoplasmic receptor.


Thanks grin

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