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usmleasr
Forum Guru Topics: 105 Posts: 970 |
what is fractional excretion of sodium? what are the differences between pre renal and renal failure?
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sudipto1973
| Forum Newbie Topics: 4 Posts: 31
Fractional excretion of sodium is excreted load of sodium divided by filtered load of sodium or to put it in other way FeNa+ = (V X UNa+) / (GFR X PNa+) where V is urine flow rate and PNa+ and UNa+ are plasma and urine Na+ conc. In pre-renal failure due to decreased renal perfusion the kidneys try to conserve as much sodium so as to increase plasma volume and hence renal perfusion. So FENa+ will be less in pre-renal failure compared to intrinsic renal failure. I don't remember the values though.
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usmleasr
| Forum Guru Topics: 105 Posts: 970
thanks good explanation..FENa+ less than 1%is typical of pre-renal failure.. in renal (ATN)FENa+ is greater than 2% due to failure to reabsorb
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