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 Insulin and glucagon  



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Author3 Posts
  #1

In FA said that Glucagon phosphorylates ---turn glycogen Synthesis off.
If we have a patient with Hypoglucemia we neeg to increase Glucose
and Glycogen is convert into Glucose.
My question is how Glucagon turn off glycogen if we need glycoge to get into Glucose.




  #2

glucagon functions on 2 enzymes involves in glycogen metabolism
it turns off glycogen synthase i.e decreases the synthesis of glycogen when there is low glycemia while turns on glucose-6-phosphorylase which releases glucose from glycogen ...increases glycemia


  #3

yeah,glucagon turns off glycogen synthesis in post absorptive state
n promotes glycogenolysis thus producing glucose.





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