Prep for USMLEPrep for USMLE
         Forum      |     Resources New Posts   |   Register   |   Login

 Duchene's Muscular Dystrophy  

Post Reply  
  • 0/5
  • 1
  • 2
  • 3
  • 4
  • 5

Author6 Posts

If a girl is diagnosed with Duchene's, how do you think she got it?


unfavourable lyonization smiling face


"usmleasr" wrote:
unfavourable lyonization smiling face

can you explain what is it ?


duchene is a X-linked disorder women are not affected normally...becos they have one normal X and 50 % maternal are inactivated at random...but it may happen in such a way most of normal X chromosomes are converted to barr body...(unfavourable lyonization..) in which case the female may express the disorder.. 8)


thanks usmleasr..



It seems rare cases of DMD in females are caused by X-chromosome autosome translocation ..resulting in disruption of dystrophin rise to female who is heterozygous for DMD gene but phenotypically express the disease ....??

Bookmark and Share

This thread is closed, so you cannot post a reply.

Login or Register to post messages

show Similar forum topics

Muscular Dystrophy( genetics)
Duchenne's muscular distrophy?
show Related resources

Digitaldoc's blog - USMLEtoMD
Pharmacology: Lippincott's Illustrated Reviews
Biochemistry: Lippincott's Illustrated Reviews

Advertise | Support | Premium | Contact