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A bacterial mutant grows normaly at 32 C but at 42 C accumulates short segments of newly synthetized DNA. Whith of the following enzymes is most likely to be defective in this mutant?

a: An endonuclease
B: DNA polymerase
c: An exonuclease
d: Helicase
e: DNA ligase


is it e: DNA ligase :roll:


A..excision endonuclease.Its due to increase in temperature(heat).

If iam wrong plz do explain the answer.


DNA ligase


yes the correct one is DNA ligase because short segments of new DNA that accumulate at 42 C are okazaki fragments and the usually are join together by the DNA ligase, whish is probably temperature sensitive in the mutation. in addition if the ligase is not working, okazaki fragment would not be joined in the replication phase.


thanks smiling face

that was a good Q :idea:

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