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 Ischemic Changes  

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A scientist wishes to study free radical production under ischemic conditions. He decides to produce cerebral ischemia by tying off an artery of the brain. Ligation of which of the following arteries would be most likely to produce significant ischemic damage?

A. Anterior cerebral artery at its origin from the internal carotid artery
B. Anterior communicating artery
C. Middle cerebral artery at its origin from the internal carotid artery
D. Posterior cerebral artery at its origin from the basilar artery
E. Posterior communicating artery


assuming that most vulnerable to ischemia area is hippocampus - pca - D.




C. major supply to brain, surface area.


C, middle cerbral artery.


new_n_post what is the answer.


"C" most area of isque..


Its a Simple Question of Anatomy

The correct answer is C. The circle of Willis is a series of arterial anastomoses that circle around the pituitary stalk at the ventral surface of the brain. If any of the vessels of the circle of Willis become blocked, blood can be routed through the remaining vessels. The object of this question is to determine which vessel does not belong to the circle of Willis. Of the options listed, only the middle cerebral artery does not belong to the circle, and instead courses laterally to supply the entire lateral convexity of the brain. Therefore, ligation of this vessel would produce the most ischemic damage.


Yea agreed. They do this kind of research, among others, in columbia. First remove an eye, then ligate 3 major arteries. but ofc middle cerebral is ligated. This kind of research is very cruel though.





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