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i read this same question both in kaplan qbank and kaplan biochemistry book but with different is question.

1: a man is a known heterozygous carrier of a mutation that causes hemochromatosis (autosomal recessive disease). suppose that 1% of the general population consist of homozygous carrier for that mutation.if the man mates with the somebody from general population. what is the best estimate for the probability that he and his mate will produce a child who is an affected homozyhote?

A. 0.025
B. 0.05
C. 0.09
D. 0.10
E. 0.25
answer in qbank b

and same question in kaplan biochemistry kaplan lecture notes but with different options as below.
A. 0.025
B. 0.045
C. 0.09
D. 0.10
E. 0.25
answer in kaplan lecture notes book is b

i cannot understand why same question have different answers?
please can some body explain correct answer with explaination.


there is no such thing as HOMOZYGOUS CARRIER


  • there is no such thing as HOMOZYGOUS CARRIER.
  • 0.05 is not much different from 0.045....

U r supposed 2 choose the best option not hunt for the exact answer !!!
Chill now.


this question had good discussion


sorry.i wrote homozygous carrier. it is 1% homozygous.

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