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 hypercalcemia in granulomatous diseases  

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can any one explain how monocytes in granuloma cause increasein 1-alpha- hydroxylse and as a result hypercalcemia


1 alpha hydroxylase is seen in kidney for production of vit.D3(1,25 dihydroxy cholecaciferol)...i guess these monocytes must be carrying the same enyme???

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