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 pernicious anemia  



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Author5 Posts
  #1

most common antibody associated with PA.
true or false------ vit B12 def causes PA
PA is associated with chronic atrophic gastritis and hence there is increased risk of gastiric ca.(true or false)




  #2

pernicious anemia is a cause of B12 deficiency.
And yes ,atrophic gastritis predisposes to adenocarcinoma of stomach.


  #3

The Ab in PA is anti-intrinsic factor.


  #4

there are three abs in PA patients: 75 % have blocking ab,50 % have binding abs and 90% have canalicur abs which is on gastric prietal cells
for more detail please refer to robbins patho( megaloblastic anemia section)
I thought this might be a usmle type qs.sinc they like to ask qs which give us this feeling that we know the topic but but want us to know even deeper


  #5

thanks for telling us about diff.antibodies





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