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 Question on Insulin vs Glucagon Phosphorylase  



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Author3 Posts
  #1

Can someone please explain to me how Glucagon turns phosphorylase ON and Insulin turns phosphorylase OFF?




  #2

First, please rephrase your question if possible.....sounds a bit redundant.....I am assuming that you are talking about glycogen phosphorlase?!? Well of course glucagon turns it ON because you need to convert glycogen to glucose and vise versa....Not too sure if I answered your quesiton?!?
MAC


  #3

they do so through phosphorylation and dephosphorylation of the enzayme glycogen phosphorlase..
GLUCAGON activate the enzyme glycogen phosphorylase through adding the phosphate to by the action of protein kinase A..
INSULIN made the enzyme less active by dephosphorylating it.. if i couldn't expalain it clearly refer to kaplan medical bio. 2004 page 137





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