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smal Forum Guru Topics: 141 Posts: 723	Oct 28, 2006 - 9:23 AM       #1 m-RNA of a malfunctioning protein is shown below, 5'-ACGCUACCAUUGUAACAAGUUAGCUAG-3' what is the t-RNA anticodon corrosponding to it. A.5'-AAC-3' B.5'-AUC-3' C.5'-UCG-3' D5'-GCU-3' E. 5'-CAA-3' PLZ mention ur reasoning too,thanks
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doc179 Forum Guru Topics: 67 Posts: 1213	Oct 28, 2006 - 6:04 PM       #2 Hi smal just an enquiry..have you quoted this question word for word? The reason I ask is there is no tRNA anticodon for an mRNA, there is a tRNA anticodon for each codon in the open reading frame of the mRNA. So the question seems incomplete. Others: please correct me if you saw enough information in the question to answer it.
HILFIGER Forum Elite Topics: 26 Posts: 235	Oct 29, 2006 - 10:25 AM       #3 Agree
smal Forum Guru Topics: 141 Posts: 723	Oct 29, 2006 - 12:35 PM       #4 dear doc 179 and HILFIGER,i quoted the qt word to word,i cross-checked it.the only thing missing is an arc made below the first 3 bases. the ans they mention is E.THE EXPLAINATION i couldnt follow,so i posted the qt
doc179 Forum Guru Topics: 67 Posts: 1213	Oct 29, 2006 - 1:51 PM       #5 I might be shooting off at a tangent here, but here is what I found. It might or might not be the answer. UUG and GUG are alternative start codons (mostly in prokaryotes). So if the UUG in the sequence is where the translation begins, it will be with the tRNA with anticodon CAA. If the first AUG got converted to ACG (if that is what the arc means) then translation could not start there. If translation then starts at UUG, you would get a protein that is 3 amino acids short. Probably that is why it malfunctions. Please post the explanation given. Am I even on the right track?
mytime Go Marching in! Topics: 40 Posts: 3161	Oct 30, 2006 - 7:07 AM       #6 Excellent........makes so much sense.

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