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 splenic sequestration  



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Author3 Posts
  #1

hi, what's the difference between splenic sequestration and splenic infarction in sickle cell disease? both are caused by blocking the vessels in spleen, right? difference?




  #2

splenic sequestration is caused by intrasplenic trapping of rbcs causing a precipitous fall in hb level and potential for hypovolemic shock.

splenic infarction is necrosis in the spleen due to interrupt of blood flow (vascular occlusion).



  #3

most sicklers have infarcted their spleen and it undergoes autosplenectomy by the time they are 6 years old. that is why they are at risk of infections with encapsulated organisms after that, coz they no longer have a functioning spleen.





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