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Hox Forum Newbie Topics: 8 Posts: 19	Oct 03, 2006 - 6:13 AM       #1 Triplet repeat expansions (CGG) in Friagile X syndrome interferes by? A.decreasing mRNA synthesis B.increasing mRNA synthesis C.creating splicing defect D.?
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blueocean Forum Senior Topics: 15 Posts: 190	Oct 03, 2006 - 3:04 PM       #2 A- When more than 200 CGG repeats are present, there is a high likelihood that the promoter region of the FMR-1 gene will be hypermethylated. When hypermethylation occurs, the enzyme necessary for transcription is unable to bind to the promoter region and initiate transcription. The end result is that no messenger RNA is produced, a condition referred to as ³transcriptional silencing² of a gene.
Hox Forum Newbie Topics: 8 Posts: 19	Oct 04, 2006 - 8:15 PM       #3 Thank you blueocean.
young_doc Forum Guru Topics: 59 Posts: 718	Oct 05, 2006 - 3:30 PM       #4 good stuff..thanks!
Topics: Posts:	Oct 09, 2006 - 1:07 AM       #5 nice.. didn't know that thanks

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