|Prep for USMLE|
|         Forum      |     Resources||New Posts   |   Register   |   Login||»  |
What is triple screen (for diagnosis of down's syndrome) ?
Triple screen tests for: beta HCG, placental estrogen, and alphat-fetoprotein. It will be positive in cases of neural tube defects (anencephaly, spina bifida) or in some chromosome abnormalities (Down's)
High AFP correlates with a neural tube defect
High estrogen and beta HCG but low AFP indicate possible chromosome abnoramlity.
The test is about 50% specific, and an amniocentesis is the test of choice for the confirmatory chromosome test, while I believe ultrasound tests for the neural tube defects.
This thread is closed, so you cannot post a reply.
| Similar forum topics|
Most imp risk factor for Down syndrome:
| Related resources|
Digitaldoc's blog - USMLEtoMD
Pharmacology: Lippincott's Illustrated Reviews
Biochemistry: Lippincott's Illustrated Reviews
Advertise | Support | Premium | Contact