Prep for USMLEPrep for USMLE
         Forum      |     Resources New Posts   |   Register   |   Login





 Down's syndrome  



Post Reply  
  • 0/5
  • 1
  • 2
  • 3
  • 4
  • 5


Author3 Posts
  #1

What is triple screen (for diagnosis of down's syndrome) ?




  #2

Triple screen tests for: beta HCG, placental estrogen, and alphat-fetoprotein. It will be positive in cases of neural tube defects (anencephaly, spina bifida) or in some chromosome abnormalities (Down's)

High AFP correlates with a neural tube defect
High estrogen and beta HCG but low AFP indicate possible chromosome abnoramlity.

The test is about 50% specific, and an amniocentesis is the test of choice for the confirmatory chromosome test, while I believe ultrasound tests for the neural tube defects.


  #3

yes right.
Thanks idopathic smiling face





Bookmark and Share



This thread is closed, so you cannot post a reply.



Login or Register to post messages








show Similar forum topics

Most imp risk factor for Down syndrome:
Down syndrome
Down Syndrome
show Related resources

Digitaldoc's blog - USMLEtoMD
Pharmacology: Lippincott's Illustrated Reviews
Biochemistry: Lippincott's Illustrated Reviews








Advertise | Support | Premium | Contact