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 which is true?  



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Author5 Posts
  #1

Kaplan says metronidazole can be safely used in preganancy including 1st trimester and UW say it's not wise to use metronidazole in the 1st trimester n look for alternatives.

any comments?





  #2

Even though metronidazole has not been found to be teratogenic, it is tumorigenic in mice and mutagenic in the Ames test. So it carries a B pregnancy rating in the 2nd and 3rd trimester and contraindicated in the 1st trimester. It is OK to use vaginally in the 1st trimester, maybe that´s what kaplan meant.


  #3

thanks juanma0. but the route of admin isn't clear in kaplan


  #4

NOTHING is clear in kaplans. Hate them.


  #5

i think a mistake was made in kaplan obs. metro is certainly not safe for use in first trimester. it may be used in second or third. a woman with candidiasis is treated with local douching until later when it can be treated.





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