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 Urology question - Critical!  

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Hi friends!

1. Regarding a 69 y/o patient with a 2 cm hard prostatic nodule on digital rectal examination, which is more appropiate way to make a definitive diagnosis of prostate cancer in this patient: prostate biopsy or serum PSA?

2. A 50 y/o patient complains from slight lower urological symptoms (mild difficulty in urination). By digital rectal examination a mass of (+1) hypertrophy can be palpated. In his family history there are cases of prostate cancer (in some relatives). What is the NEXT investigation to do in this patient?

a. Titration of serum PSA
(is it useful in such a patient? Why?)
b. Transrectal ultrasound (TRUS)
c. TRUS-guidedneedle biopsy



1. Prostate biopsy.
2. b.


1. transrectal biopsy of prostrate is more appropriate then just doing psa.Although PSA helps in dx but the most specific is the rectal biopsy

2.agree with the guest TRUS is appropriate if looking for the CA of prostrate. it will defrentiate BPH which is the hyperplasia of the transitional zone and in ca pripheral zone is involve and if us points towards the ca then biopsy and further management


1- the only way to make a defintive diagnosis is a Biopsy
2-trans Rectal US

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