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 antihypertensives Q  



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Author6 Posts
  #1

which antihypertensive drug aggravates angina and why?
a) clonidine
b) guanethidine
c) hydralazine
d) methyldopa
e) propranolol




  #2

d.

Methyldopa and my guess would be-by producing orthostatic hypotension ,but am not quite sure thats the mechanism.



  #3

hydralazine causes hypotension and "reflex tachycardia" which is not needed with diminished oxygen supply. Alpha 1 blocks cause orthostatic hypotension


  #4

Well,I read that methyldopa can aggravate angina pectoris as well...


  #5

guanethedine is the answer its a ganglion blocker so it aggravates angina


  #6

sorry ...guanethedine causes orthostatic hypotension and thats why it aggravates angina...I was out of mind I feel when I sent the last post...but the ans for ths q is guanethedine





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