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Author14 Posts
  #1

A traveler to a foreign country develops acute lymphatic filariasis
four months after his return to the United States. His symptoms include
scrotal inflammation, itching, and localized scrotal swelling and
tenderness of the inguinal lymph nodes. Which of the following immune
mechanisms does the body employ against the live filarial worms ?
A. Antibody-dependent cell-mediated cytotoxicity
B. Anti-receptor antibodies
C. Arthus reaction
D. Complement-mediated reactions
E. Deposition of circulating antigen-antibody complexes




  #2

A??


  #3

D?


  #4

a


  #5

A


  #6

A?


  #7

It's an IgE dependent cytotoxic reaction which is also caracterizes by presence of high levels of eosinophils.IgE does NOT bind complement.(IgM and IgG do)

So,my answer would be A.



  #8

in kaplan videos I remember in immunology she said IgG is the only antibody that is responsible for ADCC


  #9

http://www.cehs.siu.edu/fix/medmicro/hyper.htm
http://www.cehs.siu.edu/fix/medmicro/igs.htm


  #10

in the first link the sentence I wanted to emphasise on is the following;
Type II or Cytotoxic Hypersensitivity also involves antibody-mediated reactions. However, the immunoglobulin class (isotype) is generally IgG. In addition, this process involves K-cells rather than mast cells


  #11

ok the ans can be A as there is one document which states that there are IgG antibodies to the antigens of this worm. I am confused...


  #12

In Levinson book-you have IgE and ADCC...

I am still waiting for my ordered Kaplan,so I can not look it up over there...

But I would go with A,as it is the only thing that makes sense here.



  #13

Yes I also vote for A. Since the ADCC is mediated through IgE


  #14

Of course it is...





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