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Author4 Posts
  #1

Hi

Why is the following statement true?

mean arterial pressure and pulse pressure are both increased by an increase in total peripheral resistance in an old arteriosclerotic individual.

I thought an increase in total peripheral resistance reduces stroke volume, thereby reducing pulse pressure.

Thanks a lot.




  #2

This is my thought.
pulse pressure is the difference between systolic and diastolic pressure
The following will increase pp
1) An increase in SV
2) a decrease invessel compliance
3)Both CO=MAP/TPR and Poiseuilles equation are based on Ohms
universal law -flow =pressure /resistance
4)Id say try to remember (myself included) as a vessel stiffens that
increases pulse pressure, a compliant artery has small pulse pressure
5)Also systole and pulse pressure increase with age because compliance
is decreasing.
6) Hope this helps a little :roll:


  #3

Thanks! It's helpful.


  #4

In old age there is usually a systolic hypertension(while diastole doesn't change much)mainly due to the calcification/attherosclerotic changes in the vessel walls..The high systole and normal diastole causes increased pulse pressure.The inccreased systolic pressure also causes mean arterial pressure to increase.





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