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nico
Forum Junior Topics: 13 Posts: 37 |
Hi, I need some help regarding inulin PAH, mannitol, donot completely understand reabsorption filtration and secretion, if someone doesnot mind going into detail regarding this it has me somewhat confused. THANks
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mjl1717
| Forum Junior  Topics: 964 Posts: 5442
Filitration-plasma that enters kidneys that goes thru Bowmens capsule. mathematically its GFR times plasma conc. Secretion- As I understand is what travels from the plasma into the kidney tubules Reabsorption is what goes from the kidney tubules back to the plasma. mathematically reabsorbtion =filtration -excretion Mannitol-Retards Na andH20 reabsorbtion merely because of its osmotic contribution to the tubular fluid(Its NOT reabsorbed) PAH is used to measure effective renal plasma flow using the formula we all know uv/p.{PAH IS ONLY USED WHEN PLASMA PAH LEVELS ARE RELATIVELY LOW AND DO NOT EXCEED PAH SECRETORY Tm! Hope this helps maybe phuluong, ssrpk, or SDK can add something. By the way ssrpk congrats on your 10,000th post!
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ssrpk
| Forum Junior  Topics: 154 Posts: 2850
well thnx for tht mjl .....btw it's 1000 posts!  ofcourse there is'nt much to add......but tubular transport for most organic substances in PCT except urea shows wht we call transport maximum which can get saturated .
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nico
| Forum Junior Topics: 13 Posts: 37
thank you for your explanantion, you both have helped in clarifying this question, one more thing though, I understand tm transport, so gradient time transport is only for sodium then. Also when calculating for problem solving should you assume that since filtration fraction is 20%. If for example substance x is in plasma , we should asssume that only 20% of this gets filtered . Is that right or wrong. thankyou once again
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ssrpk
| Forum Junior Topics: 154 Posts: 2850
well u can assue filtered load to be approx. 20% for a freely filtered substance but it won't be too helpful as ff varies it's not a constant variable (depends upon renal plasma flow) filtered load= GFR X P
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