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willway Forum Junior Topics: 16 Posts: 23	Apr 17, 2005 - 7:37 PM       #1 why acetocholine has a negative inotropic effect on atria
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KEROCHI Forum Guru Topics: 60 Posts: 970	Apr 17, 2005 - 8:47 PM       #2 muscarinic receptor stimulation at SA node --dec hrt rate-neg inotropy
mjl1717 Forum Junior Topics: 964 Posts: 5442	Apr 18, 2005 - 2:16 AM       #3 Major parasympathetic neurotransmitter think-rest and digest. But I agree with K.
King Forum Senior Topics: 8 Posts: 93	Apr 23, 2005 - 12:10 PM       #4 inotropic means contractility Ach ----dec. HR throug Muscrinic R. at SAN----- -ve chronotropic however, Ach decrease contractility by decreasing intracellular calcium throug decreasing ca influx during plateu phase....."only in Atria"----- -ve inotropic
ssrpk Forum Junior Topics: 154 Posts: 2850	Apr 23, 2005 - 1:02 PM       #5 presynaptic inhibition of sympathetic nerve terminals in the ventricles
King Forum Senior Topics: 8 Posts: 93	Apr 24, 2005 - 11:14 PM       #6 Plz ssrpk tell me.... How does Ach make presynaptic inhibition of the Sympathetic N terminal to ventricle??????? :?:
ssrpk Forum Junior Topics: 154 Posts: 2850	Apr 25, 2005 - 1:05 AM       #7 M2 receptors coupled to Gi protein, however they are predominantly present in the atria but some wht also present in small amounts in the ventricles whihc probably only limits sympathetiuc activity! however with PANS it;s -ve chronotropism tht is more important!
King Forum Senior Topics: 8 Posts: 93	Apr 26, 2005 - 12:15 AM       #8 Mmmmmm,,,,Thanks ssrpk

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