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In an experiment, surgical wound sites are observed following suturing. An ingrowth of new capillaries is observed to occur within the first week. A substance elaborated by macrophages is found at the wound site to stimulate this capillary proliferation. Which of the following substances is most likely to have this function?

A Platelet-derived growth factor

B Phospholipase C-gamma

C Fibronectin

D Fibroblast growth factor

E Epidermal growth factor

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