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ssrpk Forum Junior Topics: 154 Posts: 2850	Mar 08, 2005 - 7:09 PM       #1 Why does a pulmonary embolism leads to inc. A-a gradient....? Va/Q mismatch occurs(>0.8) ... but still there is no shunt effect so why does PaO2 decrease, if ventilation is normal?
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elisamik Forum Newbie Topics: 2 Posts: 39	Apr 01, 2005 - 12:38 PM       #2 because an emboli occupies part if not all the diameter of the blood vessel, thus increasing the oxygenation time of the blood going throught that vessel. so the blood coming from this vessel is <100% saturated, leading to inc A-a gradient.

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