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 lactic acidosis  



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Author6 Posts
  #1

name 2 drugs that may cause lactic acidosis (easy one "buy-time" Q )




  #2

AZT (by causing mitochondrial damage)
acetaminophen


  #3

Metformin
Salicylates
Is there a reference for acetominophen?????????


  #4

[quote="Moctopod"]AZT (by causing mitochondrial damage)

i know about non-nucleoside RT inhibitors that cause lactic acidosis..AZT causes megaloblastic anemia...i have to look it up for AZT


  #5

Hi all

I can't remember where I first heard about acetaminophen and lactic acidosis. Maybe in Step Up? Just had a look on the Net and www.emedicine.com/emerg/topic291.htm lists it. The proposed mechanism is that the acidosis is secondary to poisoning of hepatic lactate uptake and metabolism.

Hope it helps!
Moc


  #6

one is metformin and other is mmmmmmmmm i dont know





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