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Mars-Aris Forum Elite Topics: 71 Posts: 259	Nov 19, 2004 - 10:10 AM       #1 how would a pathologist distinquish a peripheral blood smear between a patient with G6PD def and pyruvate kinase def ?
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anatomy Forum Guru Topics: 101 Posts: 423	Nov 19, 2004 - 11:14 AM       #2 G6PD def(HEINZ BODIES PRESENT) pyruvate kinase def (NO HEINZ BODIES)
Mars-Aris Forum Elite Topics: 71 Posts: 259	Nov 19, 2004 - 1:55 PM       #3 correct
Topics: Posts:	Nov 19, 2004 - 4:48 PM       #4 also bite cells....present in G6PD def.
niti Forum Guru Topics: 36 Posts: 499	Nov 19, 2004 - 6:11 PM       #5 G6PD deficiency: 1) HEINZ BODY --> Screening test during active hemolysis 2)RBC enz analysis-->Confirmatory test when hemolysis has subsided 3)Peripheral Blood-->bite cells,reticulocytosis Pyruvate kinase deficiency: 1)Confirmatory Test-->RBC enz assay. 2)Reticulocytosis,RBCs with Thorny projections.
Sakaki- Forum Senior Topics: 1 Posts: 238	Nov 22, 2004 - 8:49 AM       #6 Over here, an enzymatic test is used as the screening test. Those with G6PD deficiency will fail to oxidize the dye (no colour change). Echinocytes are seen in PK deficiency.

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