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1. Thiazides are the most frequently used diuretics for treating hypertension. They lower blood pressure by:

A. Decreasing the intravascular volume.
B. Decreasing the peripheral vascular resistance by direct action on vascular smooth muscles
C. Decreasing the responsiveness of smooth muscles to noradrenaline
D. All of the above
2. Which is the most appropriate diuretic for treating acute pulmonary oedema?

A. Loop diuretics
B. Thiazide diuretics
C. Potassium sparing diuretics
D. Osmotic diuretics
3. Thiazide diuretics will have a beneficial effect in all these conditions, except

A. Osteoporosis
B. Gout
C. Diabetes insipidus
D. Calcium nephrolithiasis
4. Which diuretic competes with Aldosterone and is used for treatment of Hyperaldosteronism?

A. Hydrochlorthiazide
B. Isosorbide
C. Furosemide
D. Spironolactone
5. Ototoxicity is a unique side effect of which group of diuretics?

A. Loop diuretics
B. Thiazide diuretics
C. Potassium sparing diuretics
D. Osmotic diuretics
6. Which of the following actions is related to Thiazide diuretics?

A. Hyperuricemia
B. Hyperkalemia
C. Hypoglycemia in Diabetics
D. Hypercalcemia
7. All the following diuretics will be effective in a person suffering from Addison's disease, except

A. Chlorthiazide
B. Urea
C. Spironolactone
D. Furosemide
8. Mannitol is contraindicated in all the following conditions, except

A. Pulmonary congestion
B. Cerebral oedema
C. Active cranial bleeding
D. Anuria due to severe renal disease
. Which of these is not true with regard to loop diuretics?

A. Can cause hyperuricemia (rarely leading to Gout)
B. Can cause hyperglycaemia ( May precipitate Diabetes mellitus)
C. Increase plasma level of LDL Cholesterol
D. Increase plasma level of HDL Cholesterol
10. Primary site of action of Thiazide diuretics in the nephron is:

A. Proximal tubule
B. Loop of Henle
C. Distal tubule
D. All of the above
11. Although a diuretic, Thiazides benefit by reducing the urine output in which of these conditions?

A. Nephrotic syndrome
B. Nephrogenic Diabetes insipidus
C. Diabetes mellitus
D. None of the above because urine output is always increased with diuretics.
12. Which class of diuretics is useful in reducing intraocular pressure during acute attacks of Glaucoma?

A. Loop diuretics
B. Thiazide diuretics
C. Potassium sparing diuretics
D. Osmotic diuretics
13. When resistance develops to loop diuretics in congestive heart failure, the following class of diuretics can be used.

A. Potassium sparing diuretics
B. Osmotic diuretics
C. Thiazide diuretics
D. Carbonic anhydrase inhibitors
14. Thiazide diuretics can have beneficial effect in osteoporosis/calcium nephrolithiasis due to which effect?

A. Hypercalciuria
B. Hypocalciuria
C. Hyperuricemia
D. Hyperkalemia
15. Which class of diuretics is preferred in elderly patients with isolated systolic hypertension?

A. Potassium sparing diuretics
B. Thiazides
C. Osmotic diuretics
D. Loop diuretics


Hi thanks for the questions but I am not sure about the 9 th question can you please explain,cause there is no mention about hte effect of Loop diuretics on the Lipid metabolism??


Ria - 9 IS correct. Be aware there are not too many drugs that increase your HDL.{If so that would kinda be front page info}
Also for adverse effects for LOOPS throw in -photosensitivity, bone marrow suppression,paraesthesia, -hypochloremic, hypokalemic metabolic alkalosis.


Thanks got you!


Thiazides can cause Hypercalcemia. So doesnt question 6 have 2 answers?


Snood I think you are right. thiazides can cause both hypercalcemia and hyperurecemia. Good spotting.

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