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 An oldie but goodie.  

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Author9 Posts

Knew this when I started studying and realized recently I'd forgotten it....

How can a solution be iso-osmotic but hypertonic?


Not sure but if I remember my first year physiology labs I think it is due to the presence of Urea


Awesome - want to take a gander at how?


urea is freely travelable


right, so you can start off with equiosmolar solutions, but then some urea (or some other permeable solute) can diffuse across the membrane creating an imbalance in tonicity.


yep...dont forget it...common pimping q on rounds


If the urea diffuses into the cell, wouldn't the solution then become HYPOtonic?


Hello guys,
Urea is a freely travellable substance as mdwannabe said.So it will travel across the membrane till its concentration is equal in both the compartments.Moreover it permeates very quickly.


Bluedusk,please correct me if Iam wrong.If we start with equiosmolar solutions,the travelling of urea will continue to keep them in the same state as it maintains an equal concentration in both of them,so much so that it does not contribute to the osmolar calculations.

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