differences between hemochromatosis & hemosid

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differences between hemochromatosis & hemosid

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11 Posts

namf
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07/13/04 - 09:20 AM

hi all,

Who can say what the important differences between hemochromatosis & hemosiderosis are??

Thanks!

bozhenka
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07/13/04 - 09:27 AM

Hemochromatosis is characterized by a progressive increase in total body iron stores with abnormal iron deposition in multiple organs

Hemosiderosis - deposited hemosiderin in multiple organs

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mani
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07/13/04 - 04:50 PM

hemochromatosis is parenchymal iron deposition with damage to the organ affevted
hemosiderosis is depostion of iron in the macrophages with no organ damage

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namf
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07/15/04 - 05:16 AM

Thank you both Prep4usmle scholars
grin

mdwannabe
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07/15/04 - 10:02 AM

These days they are calling Chromatosis those pts + for and recessive for C282Y or H63D gene loci on chrom 6. Other wise it is siderosis.

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asmi
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07/15/04 - 12:22 PM

"mdwannabe" wrote:
These days they are calling Chromatosis those pts + for and recessive for C282Y or H63D gene loci on chrom 6. Other wise it is siderosis.

:shock: thanks

yoga
usmlelogy professor
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08/02/07 - 08:05 AM

wrote:
hemochromatosis is parenchymal iron deposition with damage to the organ affevted
hemosiderosis is depostion of iron in the macrophages with no organ damage

thats NOT true hemosiderosis is serious & it causes organ damage

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SmokyWaters
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08/06/07 - 05:47 AM

I agree with Yoga...it doesnt have genetic diagnosis

yoga
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08/16/07 - 12:21 AM

isnt hemosiderosis causes MI by causing vascular injury & thrmbosis

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amritt786
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08/21/07 - 07:26 PM

#10

hey guys i thing chromatois genetic defect with increse iron absorbtion but hsiderosis increse intake

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efti
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08/22/07 - 12:36 AM

#11

Hi there.
When it comes to hemochromatosis / hemosiderosis - there are actually two divisions:

The first one says that hemochromatosis is the congenital genetic defect in Hfe gene on chr 6 with increased absorption of Fe (in duodenum). Hemosiderosis in that system is considered to be acquired disease (for example after recurrent blood transfusions - remember - one unit of blood 450mL brings 250mg of extra Fe to your body).
Ok. now the second system:
This one is more clinically relevant - and is expained above by mani smiling face

Hope it helps.
Aloha smiling face

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