"Dr_kholioo" wrote:
what are them !!
As far as I know there are only two forms of periodic paralysis --
Hypokalemic and
Hyperkalemic
They are genetically inherited and more likely to produce weakness in males than in females.
Are their more subtypes?
Could someone enlighten us?
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| doc26inder
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i have seen this question today as i have just started studying for USMLE recently
Hypokalemic -- patient should avoid excessive excercise ,exertion .attacks tend to occur on awakening after exercise.or after heavy meal and may last for several days .low carbohydrate diet and low salt levels may help prevent the attack as may acetazolamide. commonly associtaed with hyperthyroidism in young asian men - t/t of endocrine disorder then prevents recurrence
Hyperkelemic - treatment is Intravenous calcium gluconate (1-2 g ) or I/V frusemide (20-40 mg ) glucose or or glucose and insulin daily acetazolamideand chlorthiazide may prevent recurrence
There is one normokalemic periodic paralysis . clinically similar to hyperlkalemic but the plasma K levels remain normal during the attacks .T/T is with acetazolamide
there is defect in sodium channel gene on long arem of chromosome 17
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