yeti00
Forum Newbie
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FYI-This wasn't an amiguous case, but I'm unclear because I found 2 different explanations, 1 in BRS, 1 in First Aid so if anyone can clarify which is actually the correct answer/explanation.
Q: Patients with xeroderma pigmentosum are particularly sensitive to sunlight and prone to developing skin cancer because their skin cells cannot repair damaged DNA. The most common form of this genetic disorder is a result of the absence of which of the following enzymes?
A: DNA Helicase
B: DNA polymerase III
C: Endonuclease
D: RNA polymerase
E: Topoisomerase
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| mash
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c excision endonuclease
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| yeti00
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So that's what FA says, but I also read that it was a lack of ERCC-3 helicase in BRS...
http://www.rzpd.de/cgi-bin/cards/carddisp?ERCC3
So, is this a question of endonuclease being the "main" enzyme deficiency?
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| mash
Forum Fanatic
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XP is due to an excision endonuclease def which is DNA repair enzyme.
gene is ERCC ..... the enz is endonuclease and not helicase.... so, as per ur ques ans wud be endonuclease.
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I hear and I forget. I see and I remember. I do and I understand.
--Confucius
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| kalsam
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agree with mash..very well explained in kaplan..!!!
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