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Author6 Posts
  #1

hi guys ......

i would like to ask if you got a case of heparin induced thrombocytopenia within 4 days of initiating therapy and the patient is asymptomatic , platelet 90,000 / dl
PT 17 , PTT 60

what is the best next step ?

a- stop heparin and start warfarin
b- stop heparin
c- stop heparin and give platelet transfusion
d- continue heparin and observe the patient


  #2

ya stop heparin...dont give warfarin...we dont give ne kind of anticoagulant...unless its a Dirtect Thromin inhibitor.


  #3

Strictly speaking, HIT 1 is a benign condition that should normalize with continued heparin therapy, so no intervention is needed. However, it's HIT 2 that is immune-mediated and therefore thrombogenic, so stop heparin and begin therapy with a DTI. I believe the differential in time frames is within 2 days for HIT 1 and after 4 days for HIT 2.


  #4

ok guys i thought and answered as u said , but kaplan says that type 1 is benign and self limited and u can continue and observe only as its self limited and plt count will rise again .... i dont know how to answer this in real exam

beside that in type 2 hit we immediately stop heparin and start direct thrombin inhibitor

so if we treat both the same , why we would say type 1 and type 2 ????
i know type 1 is non immune and type 2 is immune mediated but the end result will be the same ??? does this make any sense


  #5

thank u fred33


  #6

Thanks fred.

can you guys give us your verdict on how to deal with HIT now?


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