namf
Forum Elite
Topics: 80
Posts: 312
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Hi everyone,
This one drives me nuts. Can someone please tell me how to study nephritic/nephrotic syndromes w/o becoming neurotic??!!
The issue for me starts of page 271 in my FA 2001. This glomerular pathology stuff has been a pain in the kidney to learn. I made 2 mnemonics, and if I don't say so myself, I think they're good (though not perfect). I will explain below. But first, if anyone has any good ways of keeping track of all this junk--please share it! I know that it's unlikely. It's like the thyroid stuff I have been dreading, and the brain tumors, and the ALL, CLL, etc from hematological problems, the pituitary front and back's hormones/acidophils/basophils/etc: just a whole bunch of glorified memorization that I can't stand/not too good at (?). Thanks for any help.
Now, my mnemonic for the nephrOtic syndromes--the ones FA teaches us are prOtein losing (btw via pathophys: when you lose protein, your liver tries to compensate by increasing its lipoprotein output--and so you get hyperlipidemia as the lipid+protein come in 1 package). Back to mnemonic: NEPHROTIC is "Lose Muscle Making Food And Drink" (for what is this muscle-making element in food and drink but PROTEIN!). Therefore
L=LSE, M=Minimal Change Dz (lipoid nephrosis), M=Membranous GN, F=Focal segmental GS, A=Amyloidosis, D=Diabetes.
For nephrItic syndromes--thinking of the I now in Inflammation, and that with inflammation there is BLEEDING: "Bleed A GRAM".Remember here that you capitalize GRAM, not BLEED b/c this about the KIDNEY--a 6 letter word, & there are both 6 nephrotic & 6 nephritic disorders discussed.
B=Berger's (IgA nephropathy), A=Alport's, G=Goodpasteur's, R=Rapidly Progressive (Cresentic) Glomerulonephritis, A=Acute Poststreptococcal GN, M=Membranoproliferative GN.
OK, granted this is imperfect: A has 3 dzs--amyloidosis in NEPHROTICS, Alport's & Acute Poststreptococcal in NEPHRITICS. M has 3 too--& they sound alike! Memranous GN & Minimal change dz in NEPHROTICS, and Membranoproliferative in NEPHRITICS (I like to think that "membranoproliferative" being such a long word compared to "membranous" is analagous to the big (or long) shock of having hematuria for NEPHRITIC dzs vs. the protein loss with it's low (or short) shock value.
There is also the problem of wether some of these dzs don't correctly belong in both categories. I will not adress this question, because I am frankly incompetent to do so--I am just following the distinctions in my FA 2001, p. 271, with blind trust. C'est mi vi.
Finally, there is the question of does it really matter to know all that!? There are still important issues of the pathophysiology of these processes, and further, the more intricate details of each dz: subEPITHELIAL lumps/humps in Acute poststrep GN, subENDOTHELIAL deposits in membranous GN; spike and dome diffuse capillary and basement membrane thickening in Membranous GN, foot process effacement in Minimal Change Dz (the most common childhood nephrotic syndrome)..
and that's just for starters.
Akkk!! I have run out of time. Any summaries, outlines, mnemonics, or other aids in novel-length (to complement the above post's size) are most welcome.
Thank you for your patience (if you're not doctor, be patient),
Namf
:roll:
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| namf
Forum Elite
Topics: 80
Posts: 312
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Ha! 1st no reply post.
I take it that everyone else finds this topic to be a massive pain as well!!
:lol:
*sorry if you're in love with kidney stuff--it's not my love...
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| mani
Forum Guru
Topics: 104
Posts: 1,403
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to be honest, reading such long posts takes a lot of time and only few people dare that!
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Sincerity and hard work are the keys to success!
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| JAS
Forum Junior
Topics: 11
Posts: 33
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namf, you really have done wonderful job. I like it. it refreshed me. :P :lol:
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| mdwannabe
Forum Guru
Topics: 37
Posts: 1,133
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namf ..as far kidney is concerned..it is far better to understand phisio behind the conditions than memorizing classifications. They will present you with symproms, and you ll need to recognize them.
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