tasneembanu Forum Guru
Topics: 96 Posts: 545
| | 07/04/04 - 01:01 PM  
 
   
 
|   #1 |
what can be detected in the window period of Hep B infection?is it only Hb core Ab or Hbe Ag also?
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| mdwannabe Forum Guru
Topics: 37 Posts: 1,133
| | 07/04/04 - 09:18 PM  
 
   
 
|   #2 |
Only HB core Ab, b/c they do not have the access to the Ag. The rest of Ab will form lattice with Ag and will be undetectible.
___________________ "Life not lived for others, is not worth living" Uncle Einstein "A life is not important, except in the impact it has on other lives" -Jackie Robinson
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| namf Forum Elite
Topics: 80 Posts: 312
| | 07/05/04 - 07:08 AM  
 
   
 
|   #3 |
For some reason, my class notes contain a +/- in the boxes for HBeAg and HBeAb--although I thought mdwannabe's explanation sounded really sensible. I think HBeAg is also in the core of the virus, by the HBcAg. Anybody explain why HBcAg never measured? Is it because it is inside the viral core and therefore usually not floating around (but I imagine the virus could fragment and expose the HBcAg--but what do I know?) Thanks!
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| mash Forum Fanatic
Topics: 147 Posts: 1,326
| | 07/05/04 - 07:39 AM  
 
   
 
|   #4 |
yeah, HBc is inside the core so, is never pr in the bld....
___________________ I hear and I forget. I see and I remember. I do and I understand. --Confucius
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| mdwannabe Forum Guru
Topics: 37 Posts: 1,133
| | 07/05/04 - 09:30 AM  
 
   
 
|   #5 |
Why don't we quickly review the dynamics of Hep B infection.. Namf...your question...so you get the hohor to go first...explain in the most simple terms...just the way you see it in your head. We shall all jump in once you done.
___________________ "Life not lived for others, is not worth living" Uncle Einstein "A life is not important, except in the impact it has on other lives" -Jackie Robinson
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| Sakaki- Forum Senior
Topics: 1 Posts: 238
| | 07/05/04 - 11:02 PM  
 
   
 
|   #6 |
There are HBeAg negative mutants (associated with a poorer prognosis), which is the reason for the +/- in your notes.
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