tonguo
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Topics: 29
Posts: 125
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1. an elderly man comes to the clinic with a chief complaint of chronic constipation. the history indicates that he is sedentary, lives alone, and prepares his own meals, mostly from canned food. he has non-insuin-depedent diabetes that is well controlled with an oral hypoglycemic agent, but he is otherwise in good health. physical examination reveals no obvious physical explanation for his bowel complaint. which of the following is least appropriate?
A. he should exercise by walking at least 30min a day
B. his diet should include fresh fruit and vegetable
C. he should take a phenolpthalein laxative whenever his bowels have not moved in 24 hours.
D. he should designte a specific time of day, preferably after a meal, when he can regularly spend 15 min without interruption on the toilet.
2. a drug that is used to decrease blood pressure and has analgesic and spasmolytic effects when given intrathecally is
A. atenolol
B. clonidine
C. Morphine
D. nitroprusside
E. prazosin
3. how to use %inhibition of dibucaine to measure muscle relaxing effect of succinylcholine?
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| mjl1717
Forum Hero
Topics: 959
Posts: 5,467
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1)phenolpthalein-should only be used for 10 days, can cause osteomalacia and electrolyte disturbanes.The other choices are benign
2)morhine-not really used to decrease BP,but the histaminic affects do and its a spasmolytic
3)Since succinycholine has a biphasic MOA(depolariztion then partial repolarizaiton-Id say that the % inhibition of dibucaine to measure the muscle relaxation effects probably has to do with it[inhibiting sodium channels at the nerve membrane]
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| tonguo
Forum Senior
Topics: 29
Posts: 125
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yeah, the answer to the first q is phenolphthalein. thanks for the explanation which i could not find in Katzung's. but the answer to the 2nd q is another drug. also, is dibucaine a local anaesthetic like procaine or lidocaine? any advice is appreciated.
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