namf Forum Elite
Topics: 80 Posts: 312
| | 07/02/04 - 10:39 PM  
 
   
 
|   #1 |
Hi guys, Quick q b4 hitting the sack. Read in Boards & Wards about somebody with liver dz who had increased peripheral conversion of androstenedione into estrogen. So your liver is failing and you increase your estrogen? Any phsio all-stars available to explain this pathophys..or did I mess some part of the q up!!?? Thank you very much!
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| Renegade Forum Elite
Topics: 18 Posts: 171
| | 07/04/04 - 12:34 PM  
 
   
 
|   #2 |
It's probably true, since hair changes, gynaecomastia and telangiectasis (in liver failure) are all blamed on estrogens.
___________________ «The desire to take medicine is perhaps the greatest feature which distinguishes man from animals.» W. Osler
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| mash Forum Fanatic
Topics: 147 Posts: 1,326
| | 07/04/04 - 01:51 PM  
 
   
 
|   #3 |
in liver ds(cirrhosis) estrogen and androstenediones cant be metabolized and there is peripheral conversion of androstenediones to estrogen in fat(aromatase activity) and hence increased estrogens...
___________________ I hear and I forget. I see and I remember. I do and I understand. --Confucius
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