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Kaplan Qbank USMLE



Author3 Posts
  #1

Hi guys,

Quick q b4 hitting the sack. Read in Boards & Wards about somebody with liver dz who had increased peripheral conversion of androstenedione into estrogen. So your liver is failing and you increase your estrogen? Any phsio all-stars available to explain this pathophys..or did I mess some part of the q up!!??

Thank you very much!

  #2

It's probably true, since hair changes, gynaecomastia and telangiectasis (in liver failure) are all blamed on estrogens.

___________________
«The desire to take medicine is perhaps the greatest feature which distinguishes man from animals.» W. Osler

  #3

in liver ds(cirrhosis) estrogen and androstenediones cant be metabolized and there is peripheral conversion of androstenediones to estrogen in fat(aromatase activity) and hence increased estrogens...

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I hear and I forget. I see and I remember. I do and I understand.
--Confucius







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