"mdwannabe" wrote:
I think it the osmotic pull that causes accumlation of fluid. Urea is extremely osmoticaly active.
but urea is osmotically inactive coz it can penetrate cell mem quickly. :?
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| mdwannabe
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right...so as urea level goes up...it exits the vascular compartment and eneters the interstitium, including pericardial sac...pulling water behind it.
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| mani
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no mdwannabe, what mah said seems rite and that means that urea will be equally distributedd in inra and extracellular comparment and hence its conc will be equal in all comparments, so it wont be able to exert any osmotic pressure to pull water.
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| mdwannabe
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I do not see how it contardicts my answer... So Urea goes UP... Water retained...Urea accumulates with water in compartments such as pericardium etc.
Please propose another theory, not just statements regarding urea'a ability to cross membranes.
:-)
If I was talking about osmotic pull by itself I d have to talk about hypotesion as well.. but I am not :-)
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| medical1
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cardiac temponade is the complication of uremic pericarditis so its important in end stage renal disease.mechanisms of both uremic pericarditis and temponade is uncertain.temponade maybe due to hammorrage or accumalation of serous fluid. fibrinous or collagenous.
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