hgheith
Forum Elite
Topics: 39
Posts: 268
|
Will the offspring of a SCID's pt treated with cloned normal genes inherit the normal gene?
|
| rida
Forum Guru
Topics: 109
Posts: 721
|
I dont think so because in humans they don't use cells which will be transmitted to offsprings, those are used in transgenic mice.
___________________
"If He takes you to it, He'll take you through it."
|
| mash
Forum Fanatic
Topics: 147
Posts: 1,326
|
no, bcoz wat we use is somatic gene therapy and dat doesnt pass on to offsprings..
germ line gene therapy has not been tried on humans yet.
___________________
I hear and I forget. I see and I remember. I do and I understand.
--Confucius
|
| hgheith
Forum Elite
Topics: 39
Posts: 268
|
Correct 
It won't be inherited because the cloned genes were introduced into somatic cells and not reproductive tissues, the offspring would inherit the defective allele.
our kaplan biochem review proffesor mentioned this question :wink:
|
| Quinn
Forum Elite
Topics: 63
Posts: 308
|
Good q hgheith!!!!  Just revised that concept....good to reinforce. Are you guys just starting Biochem review? What is the underlying mechanism for SCIDs? Why the infections? Which type of infections are most common?
___________________
The universe will yield to the will of the determined person.
|
| Malaysian
Forum Guru
Topics: 28
Posts: 778
|
SCID is a disorder due to numerous causes...one of which is ADA deficiency.Causes accumulation of toxic dATP.....leckocytes most susceptible to accumulation of toxic substance rendering vulnerable and ineffective.Infections in SCID can be anything from bacteria,virus,fungal and protozoas because both T and B lymphocytes are abnormal.
|
|
| |
| | | | | | |
