usmle prep
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in aerobic glycolysis??& anaerobic glycolysis??
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| black_tulip
Forum Senior
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aerobic glycolysis: 2ATP+2NADH+2pyruvate
anaerobic glycolysis: 2ATP+2Lactate
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| usmle prep
Forum Senior
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what is malate shuttle& glycerol 3 p shuttle??
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| rida
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Thats where NADH and FADH2 are used to produce ATP. If goes throught NADH, produces 3 ATP, and if glycerol 3 then FADH2 produces 2 ATP.
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| Quinn
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Which shuttle is used by NADH and which is used by FADH2?
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| kalsam
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malate shuttle--- NADH, pduces 8ATP/glucose
Glycerol-3P Shuttle ---FADH2, pduces 6ATP/glucose
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| Ahab
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Malate/Aspartate shuttle, moves reducing equivalents into the mitochondrion producing NADH, each NADH forms 3ATP thus for one mole of glucose which gives of 2M of reducing equivalents 6M ATP (2NADH) are produced if the malate shuttle is used (reducing equivalents formed before pyruvate kinase)
DHAP/Glycerol 3-P shuttle moves the reducing equivalents into the mitochondrion to produce FADH2, each FADH2 forms 2ATP therefore fore one mole of glucose which gives 2M of reducing equivalents 4M ATP (2FADH2) are produced.
Kalsam is including the 2M ATP formed by direct phosphorylation of ADP which does not take part in the shuttles
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| kalsam
Forum Elite
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Yes, u r correct Ahab!!
My inclusion of those 2 ATP's, is with regard to total ATP production from anaerobic gycolisis....with regard to specific shuttles, so as u said..
Malate/Aspartate shuttle --6M ATP + 2M ATP
DHAP/Glycerol 3-P shuttle -- 4MATP +2M ATP
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