asmi
Forum Hero
Topics: 1043
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For a pregnant lady who is Rh negative , before giving her RhoGAM we do indirect coombs test at 28 weeks .Why ? and if the result gives positive indirect coombs test ,what is next step ?
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| docdoc
Forum Senior
Topics: 20
Posts: 104
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First fetal-maternal blood contact occurs at 28th wk. Indirect coomb is done to look for any sensitization of Rh-ve mother before this period.
If mother is not sensitized already, antiD is given. If coomb is positive then anti-D has no effect as there are already Abs present. The fetus is monitored closely for fetal distress. In case of hemolysis, intra-uterine transfusions can be given. OR delivered early at 32wks after giving steroids?? am I going the right way ??
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| BellKicker
Forum Junior
Topics: 3
Posts: 49
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Agree with the above, plus:
Blueprints has a nice, sequecentiel approach:
1: Do antibody titers. If they exceed 1:16, go on to 2
2: Do a photospectometry (or something like that) on chord blood to look for bilirubin. If that's high go to 3
3: Transfuse or induce
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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Yep,
Thanks to both of you 
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